Contact Information
Office Hours
Faculty Homepage
Education
BS 1996–2000 (Messiah College)
PhD 2000–06 (Pennsylvania State University, College of Medicine)
Postdoctoral Fellowship 2006–10 (Harvard Medical School/Massachusetts General Hospital)
Visiting Research Associate 2010–11 (University of Pittsburgh)
Field
Fungal drug resistance
Courses
BIOL 203: Genetics and Development
BIOL 241: Medical Microbiology
BIOL 300: Genetics in Medicine and Nutrition
BIOL364: Immunology
Interests
Chemical resistant mutations in yeast
We have isolated yeast resistant mutants for several chemicals and identified candidate genes through whole genome sequencing. Projects in the lab involve validating the candidate genes and elucidating their mechanisms of resistance. Our current focus is on the mitochondria's role in stress response and maintenance of the mtDNA.
Publications
Kasar SN, Grandinette SA, Semelsberger SDU, and Diep CQ (2021). In situ hybridization in zebrafish larvae and juveniles during mesonephros development. Journal of Visualized Experiments 174:e62930.
Diep CQ, Mikeasky N, and Davidson AJ (2019). Development of the zebrafish pronephric and mesonephric kidneys. The Zebrafish in Biomedical Research, 15:145-150. Elsevier (ISBN: 9780128124314).
Belko MB, Stackhouse EA, and Diep CQ (2018). Molecular function of the lhx1a transcription factor. BIOS 89(2):52-57.
Denio EK, Kelly PM, and Diep CQ (2016). Protein-protein interaction analysis reveals a novel function of the lhx1 transcription factor in zebrafish. BIOS 87(2):31-38
Keshari V, Adeeb DB, Simmons AE, Simmons TW, and Diep CQ (2016). Zebrafish as a model to assess the teratogenic potential of nitrite. Journal of Visualized Experiments 108:e53615.
Diep CQ, Peng Z, Ukah TK, Kelly PM, Daigle RV, and Davidson AJ (2015). Development of the zebrafish mesonephros. genesis 53(3-4):257-269.
Eichelberger SL and Diep CQ (2014). Analysis of protein-protein interaction in zebrafish kidney stem cells. Keystone Journal of Undergraduate Research 2(1): 9-14.
Diep CQ, Ma D, Deo RC, Holm TM, Naylor RW, Arora N, Wingert RA, Bollig F, Djordjevic G, Lichman B, Zhu H, Ikenaga T, Ono F, Englert C, Cowan CA, Hukriede NA, Handin RI, and Davidson AJ (2011). Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature 470(7332):95-100.
Diep CQ and Davidson AJ (2011). Transplantation of cells directly into the kidney of adult zebrafish. Journal of Visualized Experiments 51 pii: 2725.
Swanhart LM, Cosentino CC, Diep CQ, Davidson AJ, de Caestecker M, and Hukriede NA (2011). Zebrafish kidney development: Basic science to translational research. Birth Defects Research (Part C: Embryology Today: Reviews) 93(2):141-156.
Diep CQ, Tao X, Pilauri V, Losiewicz M, Blank TE, and Hopper JE (2008). Genetic evidence for sites of interaction between the Gal3 and Gal80 proteins of the Saccharomyces cerevisiae GAL gene switch. Genetics 178(2):725-36.
Diep CQ, Peng G, Bewley M, Pilauri V, Ropson I, and Hopper JE (2006). Intragenic suppression of Gal3C interaction with Gal80 in the Saccharomyces cerevisiae GAL gene switch. Genetics 172(1):77-87.
Pilauri V, Bewley M, Diep C, and Hopper J (2005). Gal80 dimerization and the yeast GAL gene switch. Genetics 169(4):1903-14.