Thursday, February 7, 2019

OPT - CPT Workshop

10:00 AM & 2:00 PM HUB Schuykill Room

International Education Office

Ask a Nurse Heart Prevention Wokshop

HUB Conemaugh Room

Human Resources Office

Employees can bring any health-related questions to the session.  Examples may include: questions related to their medications, illnesses/diseases (for example diabetes, hypertension, etc), treatments.  Employees will also have the opportunity to meet individually with the graduate students (RNs).

The second candidate for the Athletic Director position will be on campus today.

Learn more about this visit and the search for Athletic Director.

Dr. Helen Moore, Principal Scientist at AstraZeneca, will informally meet with students and faculty.

Immunotherapies don't work for many cancer patients; but when they do work, they can work extremely well. So it is important to figure out as early as possible if a patient will be a "responder" or a "non-responder": I will present a simple mathematical model of tumor dynamics I used for tumor size data from patients. I combined the model parameters with a machine learning technique to create an early predictor of response/non-response. I will show how I validated the predictor on data sets for different cancer types and immunotherapies.  (Suitable for general audience)

Combination regimens are increasingly important as we try to combat resistance in viral diseases and cancer. How much better could patient outcomes be if we used the same drugs but changed their doses or schedules? With a mathematical model for the disease-therapy dynamics, we can apply optimal control to predict the regimen that will perform the best according a specified goal. I will explain the basic ideas of optimal control using some examples, and will discuss some of the challenges of math modeling in the biopharma industry.  (Suitable for audience with calculus background.)