Biology and Chemistry Undergraduate Research Presentation

Posted on 4/21/2015 1:55:34 PM

A laboratory section of Principles of Cell and Molecular Biology and Organic Chemistry participated in undergraduate research in spring 2015. Students from each section were paired with one another and asked to plan experiments that would probe potential small molecules to effect stem cell regeneration.

Coupling of coursework will link chemical synthesis and small molecule characterization with genomics to better understand molecular and cellular processes in fields such as regenerative medicine and cancer biology.

posterEach organic subgroup planned the synthesis of primary, secondary, and tertiary alcohols using the sodium borohydride and Grignard reactions. All synthetic products were analyzed for yield and purity using the spectroscopic techniques of NMR, GC/MS and IR. Members of the biology subgroups carried out an investigation on the effects of each alcohol in the small molecule library on aspects of stem-cell-based tissue regeneration in planarian flatworms.

The section group pairs met often outside of their laboratory periods to elucidate and discuss their findings. Members of each subgroup have produced a poster detailing their results which they will present.

The poster session detailing the outcomes of the research will be held on Wednesday, April 22, from 3:30–4:30 p.m. in the hallway of the first floor of Weyandt Hall. All are welcome to stop by!

The goals of this interdisciplinary undergraduate research project were to:

  1. Relate course material from each discipline making it more relevant to each major enrolled in each course;
  2. Introduce students to the nature of how real-world, complex projects are solved in industry and government;
  3. Foster excitement for undergraduate research.  

The integrated, interdisciplinary laboratory periods were designed by the research groups of Justin Fair and Robert Major. Anne Kondo was essential with the logistics and evaluation of the experiments. 

BIOL 202 Principles of Cell and Molecular Biology Students:

Thomas Armstrong
Kristen Baumgartner
Alexandra Bechtel
Hanna Beightley
Carlyn Brecht
Natalie Cignetti
Ashlyn Dearmitt
Lewis Dominguez
Kimberly Ghorm
Kristina Kurelja
Megan Maley
Mitchell Markunas
Alexander Mongan
Kelly Parsons
Kellsey Pieples
Samantha Richard
Brooke Saxinger
Madysen Schweers
Brianna Showman
Paul Simpson
Summer Slupe
Maddie Trego
Madison Ullman
Alexis Vollmer
Alyssa Zabicki  

CHEM 232 Organic Chemistry Laboratory Students:

Edgar Ceballos
Kelsey Claypool
Joseph Cristello
Ashlyn Dearmitt
Luke Galbraith
Sara Gustafson
Samuel Horwath
Kristen Howett
Stephanie Lazorcik
Christina Maziarz
Paul Singerman
Nicholle Williams
Stephanie Wolfe
Blake Woodyard

Department of Chemistry