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Mr. Daniel Croft

Dr. Daniel Croft Contact Information
Office Hours

Education

The University of North Carolina at Greensboro - Greensboro, NC
Master of Science - Biology, August 2004
Thesis Title: “Characterization of the Actin-Binding and Cellular Localization Activities of the Coiled-Coil Domain of MHCKA from Dictyostelium discoideum.”

The University of North Carolina at Greensboro - Greensboro, NC
Bachelor of Science - Biology, May 2003

Allegany College of Maryland - Cumberland, MD
Associate of Applied Science - Medical Laboratory Technology, May 1998

Field

Molecular Biology, Human Genetics, Medical Genetics, Molecular Pathology

Interests

My interests focus around Medical Genetics and Molecular Pathology which both are emerging disciplines in the field of medicine.  My work focuses on the diagnosis of human diseases through the development of molecular and genetic laboratory tests.  These molecular and genetic tests are used as predictive biomarkers in aiding the initial diagnosis and disease progression for human diseases and disorders such as cancer, neurological and developmental disorders, and selecting the correct medications and chemotherapeutics for treatment.  My interests in Medical Genetics also include the use of genetics to determine the susceptibility of an individual’s development of certain diseases and disorders and using that genetic information as a preventative treatment. 

Publications

Croft D., Jordan R., Shriver C., Ellsworth D., “Performance of whole-genome amplified DNA isolated from serum on high density single nucleotide polymorphism arrays.” Manuscript Accepted to the Journal of Molecular Diagnostics(1/04/2008) - #JM07-0155

Russ M., Croft D., Ali O., Martinez R., Steimle PA., “Myosin heavy chain kinase A from Dictyostelium possesses a novel actin binding domain that cross-links actin filaments.” Biochem J. 2005, December 22.

Egelhoff, T.T., Croft, D.T., Steimle, P.A. “Actin-Activation of Myosin Heavy Chain Kinase A in Dictyostelium: A biochemical mechanism for the spatial regulation of myosin II filament disassembly.” JBC. 2004, November 14.

Conference Presentations

2013 Association of Molecular Pathology, Phoenix, AZ
Laura Voeghtly , Alisha Decewicz, Daniel T. Croft Jr., Sidney Goldblatt, MD
“Validation of the AvanSci Bio Meso-1 Dissection System and novel xScisor technology for slide mounted tissue dissection”

2011 Association of Molecular Pathology, Grapvine, TX
Daniel T. Croft, Jr., Laura Voeghtly, Heather L. Patney, Craig D Shriver, Marina N. Vernalis, and Darrell L. Ellsworth
“Performance of Whole-Genome Amplified DNA Isolated from Serum and Plasma for Estimating Copy Number Variation with High Density Single Nucleotide Polymorphism Arrays”

2011 Association of Molecular Pathology, Grapvine, TX
Laura M. Voeghtly, Daniel T. Croft, Jr., Brenda Deyarmin, Marina N. Vernalis, Craig D Shriver, and Darrell L. Ellsworth
“Utility of Whole Genome Amplification for Assessing Copy Number Variation with High Density SNP Arrays from Formalin-Fixed Paraffin Embedded Tissue”

2011 San Antonio Breast Care Symposium, San Antonio, TX
Ellsworth DL, Croft DT, Jr, Field LA, Deyarmin B, Kane J, Ellsworth RE, Hooke JA, Shriver CD. Windber Research Institute, Windber, PA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Rockville, MD; Walter Reed Army Medical Center, Washington, DC.
“Congruence between patterns of microRNA expression and histologic grading of invasive breast carcinomas”

2011 San Antonio Breast Care Symposium, San Antonio, TX
Rachel Ellsworth, Dan Croft, Darrell Ellsworth, Craig Shriver
“Effect of obesity on gene expression in invasive breast tumors”

2010 San Antonio Breast Care Symposium, San Antonio, TX
Jasmine Saini, Xing Li, Leonid Kvecher, Caroline Larson, Daniel Croft, Yaw-Ching Yang, Jeffrey A. Hooke, Craig D. Shriver, Richard J. Mural, and Hai Hu
“Differential Gene Expression Analysis among Post-menopausal Caucasian Invasive Breast Cancer, Benign and Normal Subjects”

2006 International Dictyostelium Conference, Santa Fe, New Mexic D. Croft, Misty Russ, Omar Ali, Raquel Martinez, Paul Steimle
“Myosin heavy-chain kinase A from Dictyostelium possesses a novel actin-binding domain that cross-links actin filaments.”

2004 44th Annual Meeting of the American Society of Cell Biology, Washington DC
D. Croft, P. Brake, R. Martinez, M. Sharp, P. Steimle
“Studies of the Actin-Binding and Cellular Localization Activities of Myosin Heavy Chain Kinase A from Dictyostelium Reveal a Coiled-Coil Domain with Multiple Functions.”

2003 43rd Annual Meeting of the American Society of Cell Biology, San Francisco, CA
Daniel Croft, Kathy LaPoint, Thomas Egelhoff, Paul Steimle
“Dictyostelium Myosin Heavy Chain Kinase A is Activated by a Direct Interaction with Actin Filaments.”

2002 42nd Annual Meeting of the American Society of Cell Biology, San Francisco, CA
Daniel Croft, Leidy Tibaquira, Thomas Egelhoff, Paul Steimle
“Dictyostelium myosin heavy chain kinase A localizes to the actin-rich cortical structures via F-actin binding by its coiled-coil domain.”

  • Biology Department
  • Weyandt Hall, Room 114
    975 Oakland Avenue
    Indiana, PA 15705-1081
  • Phone: 724-357-2352
  • Fax: 724-357-5524
  • Office Hours
  • Monday through Friday
  • 7:30 a.m.–12:00 p.m.
  • 1:00 p.m.–4:00 p.m.